Synthesis of ethyl pivaloylacetic acid ester by Grignard coupling reaction of haloacetic acid ester with pivaloyl chloride

Chin. J. Org. Chem. ›› 1989, Vol. 9 ›› Issue (3): 236-238. Previous Articles Next Articles

用卤代乙酸酯与酰卤的格氏偶合反应合成新戊酰乙酸乙酯

张汉承;戚杨健;郭奇珍

厦门大学化学系

发布日期:1989-06-25

Synthesis of ethyl pivaloylacetic acid ester by Grignard coupling reaction of haloacetic acid ester with pivaloyl chloride

ZHANG HANCHENG;QI YANGJIAN;GUO QIZHEN

Published:1989-06-25

Abstract

Out of 4 catalysts used, AlCl3 achieved the highest yield (70%) for the title synthesis.

Key words: ACETIC ACID ESTER, COLOR COUPLERS, CATALYST, ALUMINIUM CHLORIDE, ETHYL ACETATE, HALOHYDROCARBON, COUPLING REACTION, ACYL COMPOUND, ZINC CHLORIDE, GRIGNARD REACTION

CLC Number:

O621

Cite this article

ZHANG HANCHENG;QI YANGJIAN;GUO QIZHEN. Synthesis of ethyl pivaloylacetic acid ester by Grignard coupling reaction of haloacetic acid ester with pivaloyl chloride[J]. Chin. J. Org. Chem., 1989, 9(3): 236-238.

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用卤代乙酸酯与酰卤的格氏偶合反应合成新戊酰乙酸乙酯

Synthesis of ethyl pivaloylacetic acid ester by Grignard coupling reaction of haloacetic acid ester with pivaloyl chloride

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