A review with 16 refs., on catalytic antibodies (abzymes, monoclonal antibodies raised against specific haptens), discussing their preparation and application in the development of new artificial enzymes for use in chem., biol., and medicine. The generation of haptens from model chem. compounds and carrier proteins, especially designing of model chems. for the preparation of catalytic antibodies is also discussed.6

Key words: REACTION MECHANISM, CATALYSIS, CHEMICAL REACTION, ORGANIC CHEMISTRY, BIOCHEMISTRY, MONOCLONAL ANTIBODY, ENZYMATIC, ANTIBODY