Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (5): 1297-1304.DOI: 10.6023/cjoc201911024 Previous Articles     Next Articles

Special Issue: 有机光催化虚拟合辑


陈跃峰a, 赵赫a, 程冬萍b, 李小年a, 许孝良a   

  1. a 浙江工业大学化学工程学院 杭州 310014;
    b 浙江工业大学药学院 杭州 310014
  • 收稿日期:2019-11-19 修回日期:2020-01-17 发布日期:2020-02-15
  • 通讯作者: 程冬萍, 李小年, 许孝良;;
  • 基金资助:

Coupling of Hantzsch Esters with Baylis-Hillman Derivatives via Visible-Light Photoredox Catalysis

Chen Yuefenga, Zhao Hea, Cheng Dongpingb, Li Xiaoniana, Xu Xiaolianga   

  1. a College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014;
    b College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014
  • Received:2019-11-19 Revised:2020-01-17 Published:2020-02-15
  • Supported by:
    Project supported by the Zhejiang Provincial Natural Science Foundation (Nos. LY18B020018, LY15B020004) and the National Natural Science Foundation of China (No. 21602197).

4-Alkyl Hasntzch esters are good alkyl radical storage. The preparation of multisubstituted α,β-unsaturated carboxylic acid esters under photocatalytic redox conditions by 4-alkyl Hantzsch esters and Baylis-Hillman adducts was investigated. The reaction conditions are mild and no additional additives are required. The coupling products were obtained in moderate to good yields.

Key words: visible light photocatalysis, radical addition, Baylis-Hillman adducts, 4-alkyl Hantzsch esters