有机化学 ›› 2017, Vol. 37 ›› Issue (8): 2124-2130.DOI: 10.6023/cjoc201612054 上一篇    下一篇

研究简报

钯/碳催化三唑导向C—H键活化芳基化

谢晓强, 邢运哲, 张国富, 丁成荣   

  1. 浙江工业大学化学工程学院 杭州 310014
  • 收稿日期:2016-12-22 修回日期:2017-04-03 出版日期:2017-08-25 发布日期:2017-04-21
  • 通讯作者: 丁成荣 E-mail:dingcr@zjut.edu.cn
  • 基金资助:

    国家自然科学基金(No.20702051)、浙江省自然科学基金(No.LY13B020017)、浙江省科技重点创新团队(No.2010R50018)资助项目

Pd/C Catalyzed C—H Arylation with Click-Triazoles as Removable Directing Group

Xie Xiaoqiang, Xing Yunzhe, Zhang Guofu, Ding Chengrong   

  1. College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
  • Received:2016-12-22 Revised:2017-04-03 Online:2017-08-25 Published:2017-04-21
  • Contact: 10.6023/cjoc201612054 E-mail:dingcr@zjut.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 20702051), the Natural Science Foundation of Zhejiang Province (No. LY13B020017) and the Key Innovation Team of Science and Technology in Zhejiang Province (No. 2010R50018).

以钯/碳为催化剂,三唑作为易移除导向基团,可实现苯环C(sp2)—H键活化芳基化反应.这是钯/碳作为催化剂催化导向基团促进的C—H活化芳基化反应的首例报道.该反应具有官能团容忍性好,无需银盐氧化剂,导向基团易移除等优点.

关键词: 钯/碳, 三唑, 芳基化, C—H活化

A novel protocol for Pd/C catalyzed C(sp2)—H arylation of benzamides with good functional group compatibility under silver-free conditions by using click-triazoles as a removable directing group has been first developed.

Key words: Pd/C, click-triazoles, arylation, C—H bond activation