有机化学 ›› 2018, Vol. 38 ›› Issue (1): 75-85.DOI: 10.6023/cjoc201707019 上一篇    下一篇

所属专题: 碳氢活化合辑2018-2019 庆祝吴养洁院士九十华诞专辑

综述与进展

N-环钯化二茂铁衍生物的合成和应用(英文)

Viacheslav I. Sokolov   

  1. 俄罗斯科学院有机化合物研究所 莫斯科 119991
  • 收稿日期:2017-07-17 修回日期:2017-09-06 发布日期:2017-10-11
  • 通讯作者: Viacheslav I. Sokolov E-mail:sokol@ineos.ac.ru
  • 基金资助:

    Project support by the Russian Foundation for Basic Research (No. 14-03-00467).

Synthesis and Application of N-Cyclopalladated Ferrocene Derivatives

Sokolov Viacheslav I.   

  1. Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russian Federation
  • Received:2017-07-17 Revised:2017-09-06 Published:2017-10-11
  • Contact: 10.6023/cjoc201707019 E-mail:sokol@ineos.ac.ru
  • Supported by:

    Project support by the Russian Foundation for Basic Research (No. 14-03-00467).

近年研究表明二茂铁的环钯化衍生物被广泛地应用于各类偶联反应中,比如Heck反应、Suzuki反应、aza-Claisen重排反应等.主要综述了含氮导向基的二茂铁衍生物的环钯化反应,包括通过不对称诱导或拆分手段合成具有平面手性环钯化合物,基于环金属化反应1,1'-取代二茂铁钯化物的合成,以及其在催化反应的应用.

关键词: 环钯化, 二茂铁基二胺, 二茂铁基亚胺, 对映选择性, 交叉偶联反应, Heck反应, Suzuki反应, aza-Claisen重排

Progress in the synthesis and application of the cyclopalladated derivatives of ferrocene with a donor nitrogen atom in the directing group is surveyed including the planar chirality and enantioselective catalysis of organic reactions and rearrangements. Transannular palladation has been found giving achiral 1,1'-disubstituted ferrocenes of ansa-structure. Cyclopalladated ferrocenes have been widely used as catalysts in the cross-coupling reactions (Suzuki, Heck, aza-Claisen, etc. )

Key words: cyclopalladation, ferrocenyl amines, ferrocenyl imines, enantioselectivity, cross-coupling reactions, Heck reaction, Suzuki reaction, aza-Claisen rearrangement