有机化学 ›› 2012, Vol. 32 ›› Issue (08): 1353-1358.DOI: 10.6023/cjoc201205007 上一篇    下一篇

特邀研究专题

多官能团羰基化合物的高选择性不对称氢化

马欣a, 李万方a, 范为正a, 陶晓明a, 李晓明a, 姚莹a, 诸吕锋b, 陈厚和b, 谢小敏a, 张兆国a,c   

  1. a 上海交通大学化学化工学院 上海 200240;
    b 南京理工大学化工学院 南京 210094;
    c 中国科学院上海有机化学研究所 金属有机化学国家重点实验室 上海 200032
  • 收稿日期:2012-05-07 修回日期:2012-06-18 发布日期:2012-06-20
  • 通讯作者: 张兆国 E-mail:zhaoguo@sjtu.edu.cn
  • 基金资助:

    国家自然科学基金(Nos. 20872090, 21172146)资助项目.

Study on the Highly Selective Asymmetric Hydrogenation of Polyfunctionalized Carbonyl Substrates

Ma Xina, Li Wanfanga, Fan Weizhenga, Tao Xiaominga, Li Xiaominga, Yao Yinga, Zhu Lüfengb, Chen Houheb, Xie Xiaomina, Zhang Zhaoguoa,c   

  1. a School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240;
    b School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094;
    c State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry,
    Chinese Academy of Sciences, Shanghai 200032
  • Received:2012-05-07 Revised:2012-06-18 Published:2012-06-20
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 20872090, 21172146).

简要地介绍了我们小组最近在多官能团化羰基底物的区域和立体选择性氢化方面的一些进展, 对该研究领域的继续深入应用前景进行了展望.

关键词: 不对称氢化, 羰基, 多官能团化, 化学选择性, 对映选择性

In this account, our recent progress in highly chemo- and stereo-selective asymmetric hydrogenation of some polyfunctionalized carbonyl substrates is briefly reviewed. The furtherance of the study in this field and their applications is prospected.

Key words: asymmetric hydrogenation, carbonyls, polyfunctionalized, chemoselectivity, enantioselectivity