有机化学 ›› 1991, Vol. 11 ›› Issue (4): 425-430. 上一篇    下一篇

研究论文

甾酮类化合物的碱催化自氧化反应的研究

郭佳生;梁晓天   

  1. 中国医学科学院药物研究所
  • 发布日期:1991-08-25

Studies on Base-catalyzed autoxidation of steroid ketones

GUO JIASHENG;LIANG XIAOTIAN   

  • Published:1991-08-25

本文报道了一些与三元环共轭的甾酮以及α,β-不饱和甾酮的碱催化自氧化反应。

关键词: 反应机理, 甾酮, 催化氧化, 自氧化,

Passing oxygen into a solution of cyclocholestanone derivative I in THF-DMF containing NaOH at -25?gave 48% the hydroxy carboxylic acid II. (Cyclo)cholestan- and -enones III-VI were oxidized similarly.

Key words: STERONE, REACTION MECHANISM, CATALYTIC OXIDATION, AUTO-OXIDATION, BASE

中图分类号: