有机化学 ›› 1997, Vol. 17 ›› Issue (5): 411-427. 上一篇    下一篇

研究论文

鞘氨醇的化学

黎运龙;吴毓林   

  1. 中国科学院上海有机化学研究所;生命有机化学国家重点实验室
  • 发布日期:1997-10-25

The chemistry of sphingosine

LI YUNLONG;WU YULIN   

  • Published:1997-10-25

动植物细胞中鞘脂及其代谢产物鞘氨醇等具有多种生理作用,是生命体传递信息的化学信使。鞘氨醇等的合成在有机合成界形成了一个经久不衰的热潮,应用各种新技术的合成方法不断出现。本文主要综述了鞘氨醇等衍生脂质的化学研究,特别是它们的化学合成进展。

关键词: 脂类, 有机合成, 鞘氨醇, 鞘脂

Lipids and their metabolites including sphingosine may act as intracellular second messengers which are involved in many biological process. The synthesis of sphingosine and related long chain base have aroused much scientific interest in recent years. Herein we review the chemical studies on sphingosine and related lipid derivatives, with focus on their chemical synthesis.

Key words: ORGANIC SYNTHESIS, LIPIDS

中图分类号: