Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (07): 1072-1075. Previous Articles     Next Articles

Notes

Mg(NTf)催化Friedl?nder缩合反应合成喹啉衍生物

王宏社*,曾君娥   

  1. (宝鸡文理学院化学化工系 陕西省植物化学重点实验室 宝鸡 721013)
  • 收稿日期:2009-03-23 修回日期:2010-02-09 发布日期:2010-02-23
  • 通讯作者: 王宏社 E-mail:hongshewang@126.com
  • 基金资助:

    陕西省植物化学重点实验室基金(No. 08JZ09);宝鸡文理学院重点科研项目(No.Zk064)

Mg(NTf) Catalyzed Efficient Synthesis of Quinoline Derivatives via Friedl?nder Condensation Reaction

WANG Hong-She, ZENG Jun-E   

  1. (Shaanxi Key Laboratory for Phytochemistry, Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013)
  • Received:2009-03-23 Revised:2010-02-09 Published:2010-02-23

Quinoline derivatives have been synthesized via Friedl?nder condensation reaction of 2-aminoaryl ketones with α-methylene ketones in the presence of 1 mol% Mg(NTf) at room temperature. The advantages of this method are easy work-up, mild reaction conditions, high yield and short reaction time.

Key words: Mg(NTf), quinoline derivative, Friedl?nder condensation reaction, catalysis