Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (10): 1672-1677. Previous Articles     Next Articles

Notes

三氟甲磺酸镱催化吲哚与硝基烯Friedel-Crafts反应的研究

陈永诚,陈圆圆,解正峰*,王文平   

  1. (新疆大学石油天然气精细化工教育部重点实验室 乌鲁木齐 830046)
  • 收稿日期:2010-12-21 修回日期:2011-04-02 发布日期:2011-05-03
  • 通讯作者: 解正峰 E-mail:xiezhf72@yahoo.com.cn

Friedel-Crafts Reaction of Indoles with Nitroalkenes Catalyzed by Yb(OTf)3

CHEN Yong-Cheng, CHEN Yuan-Yuan, JIE Zheng-Feng, WANG Wen-Ping   

  1. (Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education, Xinjiang University, Urumqi 830046)
  • Received:2010-12-21 Revised:2011-04-02 Published:2011-05-03
  • Contact: Zheng-Feng Xie E-mail:xiezhf72@yahoo.com.cn

The Friedel-Crafts reaction of indole with β-nitrostyrenes was co-catalyzed by Yb(OTf)3-Ligands. Application of this method led to a new approach to synthesize 3-substituted indole derivatives. There are several advantages to use the catalyst, which include mild reaction conditions, easiness to handle up and economic effects.

Key words: nitroalkenes, Friedel-Crafts reaction, indole derivatives, catalysis