Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (4): 978-1001.DOI: 10.6023/cjoc202110020 Previous Articles     Next Articles



胡家榆, 祝志强*(), 谢宗波, 乐长高*()   

  1. 东华理工大学化学生物与材料科学学院 江西省合成化学重点实验室 南昌 330013
  • 收稿日期:2021-10-14 修回日期:2021-11-25 发布日期:2021-12-15
  • 通讯作者: 祝志强, 乐长高
  • 基金资助:
    国家自然科学基金(21602027); 国家自然科学基金(11765002); 江西省自然科学基金重点(2021ACB203001)

Recent Advances in Visible-Light-Induced Decarboxylative Coupling Reactions of α-Amino Acid Derivatives

Jiayu Hu, Zhiqiang Zhu(), Zongbo Xie, Zhanggao Le()   

  1. Jiangxi Province Key Laboratory of Synthetic Chemistry, Biology and Material Science School of Chemistry, East China University of Technology, Nanchang 330013
  • Received:2021-10-14 Revised:2021-11-25 Published:2021-12-15
  • Contact: Zhiqiang Zhu, Zhanggao Le
  • Supported by:
    National Natural Science Foundation of China(21602027); National Natural Science Foundation of China(11765002); Key Project of Natural Science Foundation of Jiangxi Province(2021ACB203001)

Amino acids are an important class of biomass raw materials, which are widely used as starting materials to synthetize bioactive molecules, drugs and functional materials, and are also useful as organic catalysts or metal ligands for asymmetric synthesis. Visible-light-induced organic transformation has attracted enormous interest due to its intrinsic characteristics of sustainability and green chemistry. The use of visible-light to promote decarboxylative coupling of α-amino acids to construct various nitrogen-containing compounds has been considered as an attractive synthetic strategy. This review highlights the recent progress in photocatalytic decarboxylative coupling reactions of α-amino acid derivatives with various partners.

Key words: visible-light, amino acid derivatives, decarboxylative coupling, radical, functionalization