有机化学 ›› 1991, Vol. 11 ›› Issue (3): 265-268. 上一篇    下一篇

研究论文

β-环糊精2位碳仲羟基的选择性磺酰化

申宝剑;童林荟;张宏伟;金道森   

  1. 中国科学院兰州化学物理研究所
  • 发布日期:1991-06-25

Regioselective sulfonation of a C-2 hydroxyl group of β-cyclodextrin

SHEN BAOJIAN;TONG LINHUI;ZHANG HONGWEI;JIN DAOSEN   

  • Published:1991-06-25

本文报道了β-环糊精2位碳仲羟基的选择性磺酰化。

关键词: 紫外分光光度法, 质子磁共振谱法, 磺酰基, 反应机理, 红外分光光度法, 环糊精, 元素分析, 磺化, 酰化, 圆振二向色性

A convenient and high yield (42%) procedure has been developed for the regioselective tosylation of a C-2 hydroxyl group of b-cyclodextrin by the reaction of b-cyclodextrin with tosyl chloride in an alkaline solution The 13C-NMR, 1H-NMR, and CD properties of the product and the possible mechanism have been discussed.

Key words: REACTION MECHANISM, ULTRAVIOLET SPECTROPHOTOMETRY, INFRARED SPECTROPHOTOMETRY, PROTON MAGNETIC RESONANCE SPECTROMETRY, SULFONYL GROUP, CYCLODEXTRIN, ACYLATION, ELEMENTAL ANALYSIS, SULFONATION, CIRCULAR DICHROISM

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