SIOC English
有机化学
高级检索

有机化学 ›› 1992, Vol. 12 ›› Issue (3): 290-293. 上一篇    下一篇

研究论文

聚合物支载的硼氢化钠还原剂系统对苯乙酮的不对称还原

钟建华;蒋济隆;陈家戚;徐章煌;吴敏   

  1. 湖北大学化学系
  • 发布日期:1992-06-25

The asymmetric reduction of acetophenone with polymer-supported borohydride reducing systems

ZHAONG JIANHUA;JIANG JILONG;CHEN JIAQI;XU ZHANGHUANG;WU MIN   

  • Published:1992-06-25

被引次数

5

聚合物支载硼氢负离子还原剂Na^+[P-COO(BH~3)]^-中的活泼氢原子能用于酮的不对称还原。该试剂中加入带手性碳的羧酸或醇, 反应后生成的还原系统还原苯乙酮。

关键词: 聚合物载体, 苯乙酮, 硼氢化钠, 还原反应, 不对称, 还原剂, 手性试剂, 旋光度

Reaction of ion exchange resin D151 with sodium borohydride in glyme at 65?gives polymer-supported reagent. The polymer-supported reagent reacts with chiral acids or alcs. to provide the polymer-supported reductants. Acetophenone was reduced by the reductants in rather low enantioselectivity (less than 30.1% of optical yield).

Key words: REDUCTION REACTION, ACETOPHENONE, REDUCER, SODIUM BOROHYDRIDE, ASYMMETRY, CHIRAL REAGENT, OPTICAL ACTIVITY

中图分类号: